Very late reply but here goes......
We have Symantec Endpoint Protection, V 11.0.5...
We have 3 systems, 2 x Rel 4 1002 servers, and 1 x Rel 5 202 server.
The SEP killed the C drives on the 1002s as the C drive was only 4Gb in size.
The SEP ran on the 202 server, however we experienced issues where all voice ports would go out of service. Strangely this coincided with live update running (finished about 3Secs before the port errors).
We have removed all Symantec as a bad joke. The Call Pilots just do not like it.
The only issue I have had with virus attacks on a CP was an old Rel 1.07. Riddled, but even so, got a backup out of it and was able to rebuild.
We also have the SEP on CC^ x 2, CCMA x 2, NCC and CCT servers, and they do not seem to suffer from it.
Good Luck