Thanks Zelandakh!
to be more specific, we are a big company and have about 10,000 users who connect to our exchange, I had the one fornt-end to hadle the request and one back-end server to save the mail boxes using Exchange 2003 now I want to do the same but using 2007.
I did the Edge Transport as a Front-end and CAS,MailBox,Hub as Back-end but this setup didn't work.
so I am thinking about doing CAS,Hub as Front-end
and Mailbox,Hub,CAS as a backend but I don't know .