We have multiple locations running CS1000E (HA, SA, and Co-Res) under a mix of system releases ranging from 5.0 to 7.5.
I find that if the systems are installed and configured correctly, and the data network is properly configured, then the systems are every bit as reliable as an Option-81.
A typical site in my enterprise has the following:
1. CS1000E core consisting of:
a. One or more Media Gateways.
b. One or more PRI cards for PSTN trunking.
c. IP phone sets - 2033 for conference rooms, 1140e in newer offices, 2004p2 in older offices.
e. One COTS signaling server (HP).
f. One CPPM signaling server.
2. AudioCodes MP-114, or MP-124 SIP analog terminal adapters for Analog dial tone (fax, modems, wall-phones).
We have our Primary UCM running NRS, and our Secondary UCM running alternate NRS located in separate locations.
We are upgrading all sites to 7.5 with Aura System and Session Manager in the next couple of months.
We have a CallPilot 1005r at our headquarters that provides centralized voice mail to all of our remote offices.
All sites are networked using SIP trunks over an MPLS network.
We monitor everything with NetIQ.
We use a provisioning server and DHCP options to assign all firmware settings, including Node and TN assigment for the 1140 sets, so that a user can take one out of the box, send me the MAC address, and plug the phone in and have it up and running with no further intervention.
In the last 5 years, we have replaced 1 signaling server and a Media Gateway. Both due to internal power supply failures.