I have Macola ES installed on a Win 2K8 R2 Hyper V install.
We only use the TS install for OE, IM and AR as a published application.
Some issues that I encounter are based on screen resolution if you are creating a published application and running on a Win 7 PC. Also, the customer card seems to crash randomly when you add/change a credit card number, add an alternate shipping address or contact.