I agree with theoxyde; IntelliSense all the way. I do miss the edit-and-continue debugger, but the intelligence of IntelliSense (wow, say that repeatedly!) is just wonderful. I don't know how many times I've said something like this: "It's in the framework somewhere, I just don't know what it's called..." then I start typing something like "System." and read all the available items, and work my way down until I find what I need.
Another favorite of mine is the automatic spacing of code (and auto-complete for loops and such). I think it's made the language more readable.
Something else that really helps is using the Color-coding under Tools->Options. I edited the color-coding scheme so that things stand out more... my screen looks a little crazy compared to the typical coder's IDE, but it really has made a difference. (Try a black background with light-blue keywords, yellow string literals, and everything else white... code is much easier for me to manage when it's colored)
Anyway, that's my .02 USD.
Ben
There's no place like 127.0.0.1.