Hi Jeff,
OK, assuming your shortcut just has the FPW application name and not something like:
C:\Appdir\MYAPP.EXE -cC:\Appdir\Config.fpw
Then check to see if there is a CONFIG.FPW in your C:\Appdir\. You can open it in Notepad (it's just a text file). There may be one to many lines in here, look for any that reference a drive or directory not on (or mapped on) this workstation. The more important ones are RESOURCE, DEFAULT, PATH, and TMPFILES.
Rick