I had the same problem. My file keep growing larger at finally up to about 60GB and server crashed. I ran 4.10, 4.20, 4.20.02. Finally i am running the newest version 5.1 without problems. You may want to make sure that you are not performing software inventories. BTW, TWGSRVDS.dat is the main flat DB file where all data is stored to the best of my knowledge.
HTH - Stiddy