I know this is an old thread, but I thought this might be helpful...
You *should* be able to do what you want (winword.exe "C:\file101.doc") in a hyperlink. It works in the CR designer. However, it doesn't work in the ActiveX viewer.
I've been working on this problem for weeks with the BO support techs and this is their final response.
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I discussed this issue with my senior resources and this issue is a known issue version 10 ActiveX Viewer and has been tracked under ADAPT00311441. This adapt is not currently being worked on, and has not been fixed in the version 11 viewer either. If you still want this functionality I would request you to submit a business case. I look forward to your reply.
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