Don't know if it a lot of help, but I run Norton Internet Security 2002, Adaware, SpyBot and Popup Stopper Free Version. I find that they all stop certain things, but each also covers an area not coverd by any of the others. Even with all that, I picked up a browser hijacker, LOP.COM and had a difficult time removing it.
It's a jungle out there.
Learning-a lifetime occupation