This is a computer trying to see if you have any servers that are vulnerable to Nimda. Even if you are fully patched/not vulnerable, you are going to see these requests - and A LOT of them. My home network has over 21000 requests for cmd.exe alone in the last few days.
This is nothing to fear as long as you have no IIS servers or they are completely patched. It is the same idea as the CodeRed worm, where an infected server will scan other hosts on its own and other networks to see if they are vulnerable.
Just make sure you are not vulnerable and if it is severely affecting your network performance, talk to your upstream provider and have them block cmd.exe, msadc and readme.eml.
CodeRed scans look like this:
xxx.xxx.xxx.xxx - - [21/Sep/2001:20:50:56 -0400] "GET /default.ida?XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX%u9090%u6858%ucbd3%u7801%u9090%u6858%ucbd3%u7801%u9090%u6858%ucbd3%u7801%u9090%u9090%u8190%u00c3%u0003%u8b00%u531b%u53ff%u0078%u0000%u00=a HTTP/1.0" 404 284
Just make sure you are getting 404 HTTP status codes...
Hope this helps,
Paul