Well, thanks for the suggestions but it just got weirder (if that's a word). One of the users it was happening to always opened her spreadsheets through the Citrix Excel even though she had a desktop with Office loaded on it. When this first happened I told her to just use Excel on her local machine. Lo and behold it happened to her while running Excel on her local machine. Then she informed me that it only happens when she has one particular (and pretty big) file open and then opens another. Unfortunately, the other user with this issue (Citrix only user) opens completely separate spreadsheets. The only thing that is common between the two is that it happens when one SS is already open and then another one is opened. I've probably gone on too much here but it just keeps getting worse.