The Windows 2000 defragger (diskeeper) will not defragment the Exchange databases. You must use the command line method outlined above. NOTE: Using the command line defragmentation utility is only recommended if you absolutelymust reclaim the unused space for some reason. The background process will compact the database without reporting any change in the size of the file (as viewed in Explorer or a DOS window). However, Exchange will fill the unused space in the database file before using more disk space. Additionally, use of the eseutil is recommended ONLY by (or at the direction of) experienced persons and not for routine maintenance.
If you insist on performing a manual defrag, ALWAYS perform a backup first.
No lecture intended, just friendly advice from someone who's seen the eseutil get people in trouble.
Bob