an MSI is a compressed installation package, you could use Winstall to make the package, but in reality you'll only be wrapping your EXE file, which from your note is probably an installer in itself. Winstall has the ability to track changes in the operating system for building packages, you could take a baseline, run your setup.exe or whatever it is, then get the delta (The changes) and let Winstall generate the package from the changes.