I should add to that.
Once you get a general look and feel of what you want, you then save it as a template in dreamweaver. Then create editable regions.
One key here with regions and DW - don't be shy on adding editable regions.
I typically have the navigation panel a region, the main section one entire editable region - even if the page is split into two sides.
Give yourself room to move in other words. And spend time on that template, you can create items on the template that are inside a editable region - like the navigation for example. Later when you use the template, new pages will automatically bring that portion along. So take all the time in the world on that Template - it will serve you well as you progress.
On the flip side however, if you go back and add something inside an editable region - existing pages will not update with that - only areas outside the editable region will be updated.
"Never underestimate the power of determination"
Stuart
A+, Net+