Considering ongoing TCO as it relates to maintenance and upgrade costs, alot of companys are moving to Mitel including ours (7,000 users). We found it to be the easist system (by far) to administer. Also, there was no comparison in cost, the Mitel solution was significantly cheaper and the Mitel vendor offered free SW upgrades so long as we are under a maintenance contract.
Last but not least, Mitel just purchased Inter-Tel so we were not as worried going with a vendor that didn't quite have the name recognition that Cisco, Nortel, & Avaya. Then again, I assume this is why they were far less expensive.
Good Luck!