I don't think you can. The follwoing is from the SQL 2000 books online :
"System administrator (sa) is a special login provided for backward compatibility. By default, it is assigned to the sysadmin fixed server role and cannot be changed. Although sa is a built-in administrator login, do not use it routinely. Instead, make system administrators members of the sysadmin fixed server role, and have them log on using their own logins. Use sa only when there is no other way to log in to an instance of Microsoft® SQL Server™ (for example, when other system administrators are unavailable or have forgotten their passwords)."