Try this with Adobe Reader

lcNameExe = ['AcroRd32.exe']
loCIMV2        = GetObject("winmgmts://localhost/root/cimv2")
loProcesses    = loCIMV2.ExecQuery("SELECT * FROM Win32_Process WHERE Name = " + ['AcroRd32.exe'])
IF loProcesses.Count > 0
    For Each objProcess in loProcesses
        objProcess.Terminate(0)
    NEXT
ENDIF

Using traditional APIs and the Window caption as a starting point; something like;

in a module;

Public Declare Function FindWindow Lib "user32" Alias "FindWindowA" (ByVal lpClassName As Any, ByVal lpWindowName As String) As Long
Public Declare Function IsWindow Lib "user32" (ByVal hwnd As Long) As Long
Public Declare Function GetWindowLong Lib "user32" Alias "GetWindowLongA" (ByVal hwnd As Long, ByVal nIndex As Long) As Long
Public Declare Function PostMessage Lib "user32" Alias "PostMessageA" (ByVal hwnd As Long, ByVal wMsg As Long, ByVal wParam As Long, ByVal lParam As Long) As Long

Public Sub CloseProg(WinTitle$)

    Dim lret As Long
    lret = FindWindow(0&, WinTitle$)
    If lret Then EndTask lret


End Sub

Private Function EndTask(ByVal TargetHwnd&) As Boolean    
    
        If IsWindow(TargetHwnd) Then
            If Not (GetWindowLong(TargetHwnd, GWL_STYLE) And WS_DISABLED) Then
                PostMessage TargetHwnd, WM_CANCELMODE, 0, 0&
                PostMessage TargetHwnd, WM_CLOSE, 0, 0&
                EndTask = True
            End If
        End If
    
End Function

Oh! and here are the constants;

Public Const GWL_STYLE = (-16)
Public Const WS_DISABLED = &H8000000
Public Const WM_CLOSE = &H10
Public Const WM_CANCELMODE = &H1F

Wow!!!!  Thanks much HughLerwill!  

That really does kill it....But it made me think of something else.....is there a way for it to wait/check and see if the application I want to terminate is currently processing a job before ending it?

Thanks again for the absolutley great code!  You didn't give me anything vaue what-so-ever and I really appreciate it.  

I'll give Zografski's suggestion a try too and see what that does!

To expand on my recent question, I just realized the process I want to kill runs WORD which it leaves a open in Task Manager so I'd have to kill any objects of WORD it may have open.