Textboxes don't have Captions, they have values. You could have code in the on current event of a form that would disable and/or lock a text box.
If IsNull(Me.txtLockMe) Then
Me.txtLockme.Locked = False
Me.txtLockMe.Enabled = True
Else
Me.txtLockme.Locked = True
Me.txtLockMe.Enabled = False
End IF
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