needcoffee,
Stryder0 is correct. I'm having the exact same problem with my son's Blue's Clues game ("Blue's Treasure Hunt").
I tried to fins a way to set permissions for my son's user account to be able to write to the games .ini file, which is located in the C:\windows directory. My son's account does not have permission to write to this directory, so the game fails to load.
I then tried to figure out if there was a registry entry that told the game where to look for the .ini file, but could not find it.
So I'm also looking for a solution to allow my son's account to run this game without having to do the "Run as..." trick each time.
If anyone can help, I'd be much obliged.
Thanks in Advance,
sb