I would suggest you NOT use FrameMaker to create a box. It will be a nightmare for you.
Even PageMaker and Quark will be iffy. Especially PageMaker.
I am a labeling and packaging designer for a major medical supply manufacturer, and I suggest you get die lines from whoever is going to be your print vendor for the project. They will have a good idea of sizes of boxes and layouts. Also I would recommend using Illustrator or InDesign for your box design. You'll have much more freedom with them and be able to much more. (You can even import AutoCad drawings into Illustrator, so if you can't get a hold of a template, if you know someone handy with engineering drawings, you might be able to just use an AutoCad template.
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