I would not just delete it.
Assuming that your current SQL version is running under a folder called MACSQL or the like and that nothing in your config files are pointing to this folder I would do zip it up and burn it to a dvd. Once I was sure I had the data and could restore if necessary then delete it.
Not knowing your set up or configs and the location of other applications or reports or data and what not I can not say to simply delete it.
If you do find somehting such as some crystals or other applications that fail after the delete then you can evaluate restoring them to the new location, instead of restoring the entire macapps folder.
Andy Baldwin
"Testing is the most overlooked programming language on the books!"
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