I can't say I have, but you shouldn't have any issues as long as it's a stable installation. E.G. Decent hardware, controller environment, throughly tested etc.
Can't see any reason why not - the rest of the network will see the DC as it's own server. We used multiple VM's here for IIS and SQL without any issues.
Good Luck,
Steve.
"They have the internet on computers now!" - Homer Simpson
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