I've noticed a few posts recently talking about how their asp.net applications can't access this database file, or this directory, etc. I've also noticed that alot of people are granting access to various accounts that they may not be needing to.
If your asp.net application uses files that may not be local to your project (and even then, this may apply), then you need to grant directory persomission to the aspnet user account. This is the account that the asp.net process runs under, and if your project requies you to access an Access database, modify a text file, etc, then the permission for that directory (or file if you want to get super granular) must be set.
Hope this helps to clear up the whole permission issue.

D'Arcy
If your asp.net application uses files that may not be local to your project (and even then, this may apply), then you need to grant directory persomission to the aspnet user account. This is the account that the asp.net process runs under, and if your project requies you to access an Access database, modify a text file, etc, then the permission for that directory (or file if you want to get super granular) must be set.
Hope this helps to clear up the whole permission issue.

D'Arcy