Thats hard to say. If you are watching for changes to a file, there are many a file that Aloha updates throughout the day, and that depends on what software options you have. My 200ish fileservers are kept behind a firewall that has PCI scans regularly, with only 2 people able to request changes. Manager users are non admin, and are restricted from what websites they can visit. Office doors kept locked. Its sometimes a pain, but LanDesk is always a good choice.
At my previous job, the biggest threat we had was pocket card readers being used by less than quality servers stealing your CC information.