I don't have R4x on my machine anymore, so I don't know if all these commands are available, but this is what I was able to do very simply...
Create Agent
When should this agent run? After new mail arrives
Which Documents should it act on? By Author, */YOURCOMPANY
Then at the bottom, use to run a simple action
You can choose to move the document to a folder, mark it read, etc.
hope it helps [sig][/sig]