Thats where it gets a little hairy, and depands on what you're using it for.
Here's some info on it I found on the Web...
Windows NT multiplexes all file requests to a single server over one virtual circuit. The SMB (Server Message Block) reserves 11 bits for the file handle, resulting in a maximum of 2048 file handles per connection.
If you're running Terminal Services - 2048 can easily be not enough with 200 clients using it. They'd be limited to only 10 open files.
Either way - trying to open multiple 1Meg files on a file server should be no problem. I dont think that is the issue with the program crashing. But - then again it all depends on what you're using.
I hope this was of some help for ya..