These two line didn't work on my bash!
awk '{gsub(/\r/,"")}substr($0,2,15)~/\./||/^A{15}/||/^G{15}/||/^T{15}/||/^C{15}/||length($0)<14{next}1' gcb110_adaptor_removed.txt
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awk 'index(substr($1, 2, 10), ".")==0||index(substr($1, 1, 15)...